Uses and applications of naringin

Apr 29 2021

(1) Antibacterial: it is less effective against Staphylococcus aureus, Escherichia coli, Shigella dysenteriae and typhi than its aglycones.
(2) Anti inflammatory: 100mg / kg intraperitoneally in mice reduced paw edema.Administration of 100 mg / kg subcutaneously to rats also resulted in significant anti-inflammatory effects, which were associated with reduced capillary permeability.
(3) Antiviral: 200μµ g / ml) was very potent against vesicular stomatitis virus.Was protective against viral infection in mice, and the administered group survived significantly longer than the control group.
(4) Inhibition of aldose reductase in the eye: the inhibitory effect of the molten solution at a concentration of 10-4 mol / l was 80% in rats.This effect may be useful for the treatment of diabetic cataract.
(5) As a bitter tastant: its degree of bitter ness is equivalent to 1 / 5 of that of quinine (cinchondrine).But naringin's aglycone 7-rutinose has no bitter taste.Pummelo and sour orange bitter taste are caused by the containing products.In addition, there is a balance against peroxidation.Is also one of the flavonoids in the genus Citrus that can stimulate the oviposition of the blue crested butterfly, pupilio protenor.
(6) Can be used as raw materials for the synthesis of neohesperidin and neohesperidin dihydrochalcone.Dihydrochalcone sweeteners can be prepared by cracking the pyranone ring under basic conditions, followed by hydrogenation.
(7) When applied in small amounts, it causes swelling of the perineum and sexual hyperfunction by stimulating the spinal erectile center.